Hepatitis B Management in Special Populations

  • Author: Alessandra Mangia, MD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 6/4/18 (What's New)

Summary

  • In regions of high endemicity, most cases of HBV transmission occur in infants via perinatal transmission[Wong 2014] or horizontal transmission from infected family members
  • Hepatitis B Virus–Infected Women of Childbearing Age
    • Women with hepatitis B who are of childbearing age are likely to be in the immune-tolerant stage of disease,[Chang 1995] with high HBV DNA and normal ALT
    • Treatment should be deferred in women with immune-tolerant disease. Other women require careful history taking and a discussion of family planning as part of treatment decision making
    Hepatitis B Virus–Infected Pregnant Women
      Natural History
        Hepatitis B Virus Testing in Pregnant Women
          Hepatitis B Virus Treatment During Pregnancy for Maternal Health
            Role of Hepatitis B Virus Therapy in Preventing Transmission
              Choice of Anti–Hepatitis B Virus Agents in Hepatitis B Virus–Infected Pregnant Women
                Postpartum Follow-up

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