Hepatitis B Management in Special Populations

  • Author: Alessandra Mangia, MD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 6/4/18 (What's New)


  • An estimated 5% to 10% of global HBV infections are in HIV-coinfected patients
  • Hepatitis B is generally more aggressive in patients coinfected with HIV, with higher rates of chronicity, higher HBV DNA levels, more frequent reactivation periods, and more rapid progression to cirrhosis[Puoti 2006]
  • HBV causes significant liver-related mortality in HIV-infected patients[Weber 2006; Thio 2002]

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