Management of Hepatitis B Infection

  • Authors: Harry L. A. Janssen, MD, PhD; Milan J. Sonneveld, MD, PhD, MSc (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 5/25/18 (What's New)

Summary

    Entecavir
    • Entecavir is approved in the United States and Europe for the treatment of chronic HBV infection in patients with evidence of viral replication and either evidence of persistent elevations in aminotransferases or histologically active disease (Table 3)[FDA Entecavir; EMA Entecavir]
    • Entecavir has well-established safety and efficacy in treatment-naive patients with HBeAg-positive and HBeAg-negative disease and is associated with very low rates of resistance during longer-term use
    Tenofovir DF
      Tenofovir AF
        Adefovir
          Lamivudine
            Telbivudine
              Adverse Events

              Action required