Hepatitis Delta Virus

  • Author: Mario Rizzetto, MD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 6/1/18 (What's New)

Summary

  • HDV is a unique human pathogen dependent for infection on the hepatitis B virus
    • Patients coinfected with HDV and HBV experience more severe liver disease, more rapid progression to cirrhosis, and are more likely to experience hepatic decompensation and death vs patients infected with HBV alone
  • The exact mechanism by which HDV causes these consequences is not yet fully understood, and treatment options for patients with HDV infection are limited

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