Management of Hepatitis B Infection

  • Authors: Harry L. A. Janssen, MD, PhD; Milan J. Sonneveld, MD, PhD, MSc (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 5/25/18 (What's New)

Summary

  • Some nucleos(t)ide analogues inhibit human mitochondrial DNA polymerases, which may result in lactic acidosis, neuropathy, and myopathy
  • Most nucleos(t)ide analogues present limited risk of adverse events during the first years of therapy in patients with compensated liver disease

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