Hepatitis A Virus and Hepatitis E Virus: Different Viruses With Similar Stories

  • Author: Kenneth E. Sherman, MD, PhD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 5/17/18 (What's New)


  • HAV and HEV can each be diagnosed by testing for IgM and IgG antibodies to the relevant virus[BASSH; WHO HEV]

    • Positive IgM reflects recent infection (within the past few months) whereas a positive IgG reflects immunity and will persist even after infection is cleared
    • Positive HAV IgM is good evidence for acute infection

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