Two HAV monovaccines are approved for individuals at least 12 months of age and are highly effective when given as a 2-dose series of intramuscular injections^{[FDA Hepatitis A Vaccine; FDA Hepatitis A Vaccine, Inactivated]}

• Monovalent hepatitis A pediatric vaccine or combination hepatitis A-hepatitis B vaccine vaccines are available for use in children

The US Advisory Committee on Immunization Practices recommends routine HAV vaccination for children, travelers to endemic areas, MSM, users of illicit drugs, families of adoptees from intermediate- or high-endemicity countries, researchers working with HAV, individuals with chronic liver disease, individuals with clotting-factor disorders, and those with direct contact with HAV-infected individuals^{[CDC HAV FAQ]}