Targeted Therapies

  • Author: Gail Wilkes, RNC, ANP-BC, MS, AOCN® (More Info)
  • Section Editor: Marlene SanFilippo, MSN, ARNP, FNP-C, AOCNP®
  • Editors In Chief: Dawn Camp-Sorrell, MSN, FNP, AOCN®; Rebecca Hawkins, MSN, ANP, AOCN®, ACHPN
  • Last Reviewed: 7/9/18 (What's New)


  • Some agents inhibit more than 1 target or cellular pathway and are called multikinase inhibitors
  • Key side effects of multikinase inhibitors for nurses to assess include visual changes; skin rash; and signs of heart failure
  • Patients may experience increased toxicity due to the targeting of multiple pathways

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